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The Influence of Organic Vanadium Complexes on an Antioxidant Profile in Adipose Tissue in Wistar Rats

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dc.contributor.author Francik, Renata
dc.contributor.author Kryczyk-Kozioł, Jadwiga
dc.contributor.author Krośniak, Mirosław
dc.contributor.author Francik, Sławomir
dc.contributor.author Hebda, Tomasz
dc.contributor.author Pedryc, Norbert
dc.contributor.author Knapczyk, Adrian
dc.contributor.author Berköz, Mehmet
dc.contributor.author Ślipek, Zbigniew
dc.date.accessioned 2023-11-09T14:19:10Z
dc.date.available 2023-11-09T14:19:10Z
dc.date.issued 2022
dc.identifier.citation Francik R, Kryczyk-Kozioł J, Krośniak M, Francik S, Hebda T, Pedryc N, Knapczyk A, Berköz M, Ślipek Z. The Influence of Organic Vanadium Complexes on an Antioxidant Profile in Adipose Tissue in Wistar Rats. Materials. 2022; 15(5):1952. https://doi.org/10.3390/ma15051952 pl_PL
dc.identifier.issn 1996-1944
dc.identifier.uri http://195.117.226.27:8080/xmlui/handle/123456789/515
dc.description.abstract One of the aspects of biological activity of vanadium is its influence on carbohydrate metabolism. For more than 30 years, various vanadium complexes have been tested as antidiabetic agents. This study researched organic vanadium complexes with bipyridinium ligands and their influences on metabolic rate, as well as on the antioxidant activity of adipose tissue. The effects of sodium (2,2′-bipyridine) oxidobisperoxovanadate (V) octahydrate (known as the V complex), bis(2,2′-bipyridine) oxidovanadium (IV) sulfate dehydrate (known as the B complex), and bis(4.4′-dimethyl-2,2′-bipyridine) oxidovanadium (IV) sulfate dihydrate (labelled as the BM complex) were assessed. Solutions of the tested complexes were introduced intraperitoneally with a probe to animals fed with either a control diet or a high-fat diet. The BM complex had a significant influence on the increase in ferric reducing antioxidant power, as well as on the concentration of glutathione in the adipose tissue of rats fed with a high-fat diet. The V complex increased the concentration of glutathione in the adipose tissue of rats fed with control fodder, as well as significantly reduced the relative change in rat weight for the high-fat diet. Furthermore, the presence of each tested vanadium complex had an impact of statistically significant increase in basal metabolic rate, regardless of applied diet. Further research on these organic vanadium complexes is necessary to understand the mechanisms responsible for their ability to affect adipose tissue. pl_PL
dc.language.iso en pl_PL
dc.publisher MDPI pl_PL
dc.rights Attribution 4.0 International
dc.rights.uri https://creativecommons.org/licenses/by/4.0/
dc.subject organic vanadium complexes pl_PL
dc.subject adipose tissue pl_PL
dc.subject antioxidants pl_PL
dc.subject high-fat diet pl_PL
dc.subject metabolic rate pl_PL
dc.title The Influence of Organic Vanadium Complexes on an Antioxidant Profile in Adipose Tissue in Wistar Rats pl_PL
dc.type Article pl_PL


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